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Surface modified antimicrobial polypropylene meshes: a futuristic repair solution for hernia
Zeeshan Sanbhal1, Ahsan Ahmad Ahmad Ursani2, Muhammad Aqeel Bhutto3
1Department of textile engineering, Mehran University of Engineering & Technology, Muet Jamshoro, Jamshoro, Sindh, 76062, Pakistan.
Biomedical Physics & Engineering Express
|July 28, 2026
Summary
Surface modification of polypropylene (PP) mesh implants with drug carriers enhances antimicrobial properties, preventing infections after hernia repair. This innovation offers improved safety and efficacy for hernioplasty procedures.
Area of Science:
- Biomaterials Science
- Surgical Innovation
- Drug Delivery Systems
Background:
- Polypropylene (PP) mesh is standard for hernioplasty, offering strength and flexibility.
- PP mesh's hydrophobic nature limits antibiotic effectiveness, posing infection risks.
- Current methods lack effective infection prophylaxis in hernia repair.
Purpose of the Study:
- To review advances in surface modification of PP mesh for infection-free implants.
- To explore drug carriers and antibiotics for sustained release from PP mesh.
- To evaluate the potential of antimicrobial PP meshes in hernioplasty.
Main Methods:
- Review of surface modification techniques for PP mesh.
- Investigation of oxygen plasma treatment for surface functionalization.
- Analysis of chitosan and β-cyclodextrin as drug carriers.
Main Results:
- Surface functionalization significantly improves PP mesh properties.
- Oxygen plasma treatment is a highly effective modification technique.
- Chitosan and β-cyclodextrin demonstrate success as drug carriers on PP surfaces.
- In-vivo studies indicate positive outcomes for modified antimicrobial PP meshes.
Conclusions:
- Surface-modified antimicrobial PP meshes represent a significant advancement for hernioplasty.
- These implants offer a promising solution for infection prevention in hernia repair.
- Further development could enhance safety and efficacy in surgical procedures.
