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Updated: Aug 5, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
Published on: December 15, 2023
A multi-domain qualitative study on factors influencing access to preventive hepatitis B care among rural population
Caixia Li1, Mi Zhong2, Gengyang Yuan3
1Department of Nursing, the Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Objectives:
This study aimed to explore barriers precluding hepatitis B virus (HBV) preventive care among the rural population.
Methods:
Guided by the National Institute on Minority Health and Health Disparities framework, this qualitative study applied an interpretative phenomenological approach. Participants (n = 34) were recruited from three healthcare settings in southern China from May 2024 to January 2025. Data from semi-structured interviews were analyzed using interpretative phenomenological analysis.
Results:
Barriers spanned four domains with 11 subthemes. 1) Behavioral: the last-resort paradigm in healthcare utilization, reliance on folk remedies, and intergenerational silence in familial HBV prevention; 2) Physical environment: remote residence from healthcare facilities and compound vulnerabilities in living and working environments; 3) Sociocultural: social marginalization stemming from HBV discrimination, fatalistic resignation towards health, and the myth of the hardy survivor; and 4) Healthcare system: misperceptions, underestimated needs, and access barriers related to labor, mobility, and misaligned healthcare insurance policy.
Conclusions:
These barriers perpetuate late HBV diagnosis, low vaccine uptake, and poor treatment adherence among the rural population. This highlights the need for mobile health services to overcome geographic barriers; culturally appropriate interventions to dismantle misinformation, HBV discrimination, and myths; and policies to reduce financial burden and improve insurance coverage, thereby making HBV preventive care accessible for this marginalized group.
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