Related Experiment Video
Updated: Aug 5, 2026

08:31
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Racial Disparities in Transcatheter Edge-to-Edge Repair Versus Open Mitral Valve Surgery: A Nationwide Analysis
Ali Awad1, Qusai Al Qudah2, Joud Fahed3
1Department of Internal Medicine, Detroit Medical Center, Wayne State University, Detroit, MI, USA.
Cardiology Research
|July 29, 2026
Summary
Racial disparities persist in mitral valve interventions, with Black and Asian/Pacific Islander patients facing higher mortality. Late presentation highlights potential barriers to timely cardiovascular care for minority populations.
Area of Science:
- Cardiovascular Medicine
- Health Services Research
- Health Disparities
Background:
- Racial disparities are evident in cardiovascular care, but data on mitral valve interventions are limited.
- This study investigates racial differences in procedural selection and outcomes for mitral valve repair and surgery.
Purpose of the Study:
- To examine racial disparities in procedural selection and outcomes following transcatheter edge-to-edge repair (TEER) and open mitral valve surgery.
- To identify factors contributing to these disparities, including patient demographics, comorbidities, and presentation timing.
Main Methods:
- Analysis of the National Inpatient Sample (NIS) database from 2016-2022, including 26,456 adult patients undergoing mitral valve intervention.
- Multivariable regression models were employed to assess racial differences in mortality, procedure type, length of stay, and charges, adjusting for key covariates.
Main Results:
- Transcatheter edge-to-edge repair (TEER) constituted 89% of procedures.
- Black patients, though younger, had higher illness severity and greater odds of receiving TEER (OR=1.36).
- Adjusted analysis revealed persistent mortality disparities for Black (OR=1.49) and Asian/Pacific Islander (OR=2.20) patients. Late presentation was more frequent in Black and Hispanic patients.
Conclusions:
- Black and Asian/Pacific Islander patients experience significantly higher inpatient mortality after mitral valve intervention, unexplained by available data.
- Late referral patterns suggest systemic barriers to timely specialized cardiovascular care for minority populations.
Related Concept Videos
Mitral Stenosis III: Medical Management
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Regurgitation III: Medical Management
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...

