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Published on: July 28, 2026
Scarless Surgery: Clinical Indications for Transoral Endocrine Surgery and Implications for Pathologists
Jordan M Broekhuis1, Benjamin C James1, Raymon H Grogan2
1Harvard Medical School, Boston, MA, USA; Department of Surgery, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA.
Clinics in Laboratory Medicine
|July 29, 2026
Summary
Transoral endocrine surgery (TES) offers a scarless method for thyroid and parathyroid procedures in select patients. Further research is needed to understand how TES impacts the examination of surgical specimens.
Area of Science:
- Endocrine Surgery
- Surgical Pathology
Background:
- Transoral endocrine surgery (TES) is a minimally invasive, scarless technique for thyroidectomy and parathyroidectomy.
- Patient selection criteria for TES are established, including specific size limitations for thyroid nodules.
Purpose of the Study:
- To review the current literature on transoral endocrine surgery (TES).
- To highlight the need for further investigation into the effects of TES on surgical specimen handling and pathologic examination.
Main Methods:
- Literature review of transoral endocrine surgery techniques and outcomes.
- Analysis of reported cases concerning surgical specimen integrity in TES.
Main Results:
- TES is feasible for well-selected patients with specific thyroid nodule characteristics.
- Fragmentation of surgical specimens during TES has been noted in some studies.
Conclusions:
- Transoral endocrine surgery provides a scarless surgical option for endocrine procedures.
- The implications of potential specimen fragmentation in TES require additional research to ensure accurate pathologic assessment.
