Breast Cancer: Diagnosis (PEM) to Assessment of Treatment Response

Dedicated breast positron emission imaging modalities including planar positron emission mammography and volumetric ring-type dedicated breast PET represent advanced high-resolution molecular imaging architectures specifically designed to overcome the spatial resolution and sensitivity limitations of conventional whole-body positron emission tomography/computed tomography clinical scanners. Utilizing 2-[¹⁸F]fluoro-2-deoxy-D-glucose or emerging receptor-targeted radiopharmaceuticals, these dedicated breast systems provide highly detailed functional cartography of breast tissue with a spatial resolution of 1.5 to 2.4 mm, enabling the detection of subcentimetric primary lesions, intraductal disease components, and separate synchronous malignant foci.