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Updated: Aug 5, 2026

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
Published on: January 27, 2018
Efficacy of Intraoperative Platelet-Rich Plasma in Follicular Unit Extraction Hair Transplantation: A Prospective
Pawan V Dawane1, Vijay N Rode1, Snehal M Bharsakle1
1Department of Oral and Maxillofacial Surgery , Dr. R. R. Kambe Dental College and Hospital , Akola, Maharashtra India.
Background:
Follicular Unit Extraction (FUE) is a standard technique for hair restoration. However, post-transplant graft survival and early regrowth can be compromised by ischemic injury and delayed vascularization. Platelet-rich plasma (PRP), rich in growth factors, may enhance graft survival and follicular growth.
Aim:
To compare the efficacy of intraoperative PRP in FUE hair transplantation.
Methods:
A prospective, randomized study was conducted on 60 male patients with androgenetic alopecia. Group A (n = 30) underwent FUE with PRP, and Group B (n = 30) underwent FUE without PRP.
Results:
At 6 months, all PRP patients (100%) achieved ≥ 75% regrowth versus 40% in controls (p < 0.000001). Hair density was significantly higher in the PRP group at 1 month (66.7% vs. 16.7%), 3 months (80% vs. 43.3%), and 6 months (100% vs. 40%). Mean hair shaft length at 6 months was greater with PRP (12.3 mm vs. 8.4 mm, p < 0.0001). Scalp redness resolved faster (24 vs. 36 days, p < 0.0001) and satisfaction scores were higher (8.4 vs. 7.1, p < 0.0001).
Conclusion:
Intraoperative PRP significantly improves graft survival, accelerates regrowth, promotes faster healing, and enhances patient satisfaction in FUE hair transplantation.
