Related Experiment Video
Updated: Aug 5, 2026
Ye's Swing Technique for Small-incision Lenticule Extraction Surgery
Published on: June 27, 2025
Long-term observation of decentration in high and low-to-moderate myopia following small incision lenticule
Xiaosong Han1, Tianze Cui1, Fei Xia1
1Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, 200031, China; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, 200031, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, Shanghai, 200031, China.
Purpose:
To investigate the long-term decentration changes and associated factors after SMILE surgery for high and low-to-moderate myopia.
Methods:
47 eyes of 30 patients undergoing SMILE surgery at the Eye & ENT Hospital of Fudan University were included in this prospective study (age at surgery: 28.23 ± 7.38 years old, male:female = 13:17). 20 eyes of 15 patients were divided into low-to-moderate myopia (LMM) group, and 27 eyes of 20 patients to high myopia (HM) group by preoperative refraction. Main outcome measures included visual acuity, preoperative refraction, intraocular pressure, axial length, optical zone diameter, decentration, and ablation depth. Follow-up time was 11.50 ± 1.52 years (10 to 13 years).
Results:
All surgeries were successful without complications. The safety index was 1.18 ± 0.17 in HM group and 1.19 ± 0.17 in LMM group. The decentration was 0.38 ± 0.20 mm in HM group and 0.48 ± 0.19 mm in LMM group, with no statistically significant difference between groups (p = 0.130). In LMM group, decentration was negatively correlated with spherical refraction (r = -0.46, p = 0.016*) and spherical equivalent (r = -0.41, p = 0.032*), and positively correlated with corneal thickness (r = 0.50, p = 0.008*) and axial length (r = 0.51, p = 0.006*). In HM group, no significant correlation was found between decentration and evaluated factors (p > 0.05).
Conclusion:
SMILE surgery demonstrates long-term safety, efficacy, and predictability. Long-term decentration after SMILE is unaffected by the degree of myopia.
