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Published on: January 7, 2019
Hexagonal Hollow-Core Photonic Crystal Fiber for High-Sensitivity Terahertz Glucose Detection
Mohammad Abdullah-Al-Shafi1, Shuvo Sen2, Mashiyat Mubassera3
1Faculty of Science and Engineering, Southern Cross University, Gold Coast, Australia.
Journal of Biophotonics
|July 30, 2026
Summary
A new hexagonal photonic crystal fiber sensor offers noninvasive urine glucose detection for diabetes management. This cost-effective device shows high sensitivity for early diabetes screening and continuous glucose monitoring.
Area of Science:
- Photonics
- Biomedical Sensing
- Optical Fiber Technology
Background:
- Diabetes mellitus is a growing global health issue with severe complications.
- Current glucose monitoring methods can be invasive or lack sensitivity for early detection.
Purpose of the Study:
- To develop a novel hexagonal photonic crystal fiber (HPhCF) sensor for noninvasive urine glucose detection.
- To evaluate the sensor's performance across various glucose concentrations for diabetes screening.
Main Methods:
- Design and fabrication of a hexagonal photonic crystal fiber (HPhCF) sensor.
- Testing the sensor's response (RS performance) to different urine glucose concentrations (0-15 mg/dL to 10 g/dL).
Main Results:
- The HPhCF sensor demonstrated high refractive sensitivity (RS) values, consistently above 95%.
- Sensitivity showed a gradual decrease with increasing analyte concentration, maintaining high performance.
- The sensor design is compact, fabrication-friendly, and compatible with existing methods.
Conclusions:
- The proposed HPhCF sensor is a promising low-cost, highly sensitive tool for noninvasive glucose monitoring.
- It has strong potential for early-stage diabetes screening and continuous glucose monitoring in biomedical applications.

