Cardiovascular-Kidney-Metabolic Syndrome: Models of Care

Area of Science:

• Internal Medicine
• Nephrology
• Cardiology
• Endocrinology

Background:

• Cardiovascular-kidney-metabolic (CKM) syndrome involves interconnected cardiovascular disease (CVD), chronic kidney disease (CKD), and metabolic disorders.
• These conditions share risk factors and mechanisms, leading to organ dysfunction, increased morbidity, and mortality.
• Current disease-specific care models are inadequate for managing CKM syndrome's complexity.

Purpose of the Study:

• To review evidence on multispecialty clinics and interventions for improving care in CKM syndrome.
• To highlight the need for coordinated, patient-centered, and multidisciplinary approaches to CKM care.
• To explore how digital health, precision medicine, and analytics can support integrated CKM care models.

Main Methods:

• Synthesis of available evidence on multispecialty clinics and interventions.
• Review originated from an International Society of Nephrology Transplant Sister Center Meeting.
• Focus on improving care for patients with multiple CKM comorbidities.

Main Results:

• Traditional, fragmented care models lead to delayed treatment and poorer outcomes.
• Integrated CKM care models require cross-specialty collaboration, data sharing, and shared decision-making.
• Digital health and precision medicine offer potential for improved risk stratification and personalized interventions.

Conclusions:

• New care models are essential to address the integrated nature of CKM syndrome.
• Multidisciplinary, patient-centered approaches are crucial for optimizing treatment.
• Future CKM care should leverage technology for enhanced monitoring and personalized interventions.