Related Experiment Video
Updated: Aug 5, 2026

Enhanced Sample Multiplexing of Tissues Using Combined Precursor Isotopic Labeling and Isobaric Tagging (cPILOT)
Published on: May 1, 2017
The Forge AHEAD Center Pilot Plus program: An integrated framework combining pilot funding, training, and
Michael Mugavero1, Rikki M Tanner1, Trudi V Horton1
1The University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL, USA.
The Deep South faces high rates of chronic diseases. The Pilot Plus model integrates funding, training, and community engagement to build a diverse research workforce and address health disparities.
Area of Science:
- Translational Science
- Public Health
- Cardiometabolic Health
Background:
- The Deep South exhibits the highest prevalence of obesity, diabetes, and hypertension in the U.S.
- Significant disparities in these conditions exist based on race, socioeconomic status, and rurality.
- Addressing these health disparities necessitates a skilled translational science workforce capable of implementing scalable, real-world solutions.
Purpose of the Study:
- To establish the Forge AHEAD Center aimed at improving cardiometabolic health outcomes in the Deep South.
- To advance research and develop a scientific workforce equipped to tackle regional health challenges.
- To introduce the "Pilot Plus" model as an integrated framework for research and workforce development.
Main Methods:
- The "Pilot Plus" model integrates pilot funding with structured training in translational science.
- It incorporates multidisciplinary team-based mentorship and embedded community engagement.
- Provides early-stage investigators access to expertise in dissemination, implementation science, and social determinants of health.
Main Results:
- The Pilot Plus model addresses fragmentation in traditional research development by aligning funding, training, and infrastructure.
- It expands access to critical resources across multiple institutions.
- Facilitates the incorporation of community stakeholders into the research process.
Conclusions:
- The Pilot Plus model offers an adaptable framework for enhancing translational research capacity in the Deep South.
- It aims to develop a demographically diverse group of investigators prepared to improve health outcomes.
- This approach is crucial for regions burdened by high rates of chronic diseases.
Related Concept Videos
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Preclinical Development: Overview
Improving Translational Accuracy
Improving Translational Accuracy
Pilot and Numeric Relaying
PI3K/mTOR/AKT Signaling Pathway

