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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Synchronized left anterior/posterior fasciculars pacing - a modified strategy for difficult left ventricular lead
Yao-Zong Guan1, Tang Zhang1, Huan-Jie Huang1
1Department of Cardiology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China.
Insights
This study presents a novel bailout strategy for cardiac resynchronization therapy-defibrillator (CRT-D) implantation in patients with challenging left ventricular lead placement. The approach successfully reduced QRS duration and improved patient quality of life.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Cardiac resynchronization therapy-defibrillator (CRT-D) is effective for ischemic heart failure (HF).
- Left ventricular lead implantation poses significant challenges in CRT-D procedures.
- Complete right bundle branch block (cRBBB) can complicate CRT-D lead placement.
Purpose of the Study:
- To describe a novel bailout approach for difficult left ventricular lead implantation during CRT-D.
- To evaluate the efficacy of this alternative pacing strategy in a patient with ischemic cardiomyopathy and cRBBB.
- To assess the impact on QRS duration and patient outcomes.
Main Methods:
- A patient with ischemic cardiomyopathy and cRBBB underwent CRT-D implantation.
- Conventional left ventricular lead placement in the lateral/posterior wall was unsuccessful.
- A bailout strategy involving right ventricular lead implantation in the anterior and posterior septal regions was employed.
- Synchronized pacing of the left anterior and posterior bundle (LAB and LPB) was performed.
Main Results:
- Successful implantation using the bailout approach.
- Significant reduction in QRS duration from 160ms to 100ms.
- Improved patient quality of life and stable pacing parameters at one-month follow-up.
Conclusions:
- This case demonstrates a technically feasible bailout approach for CRT-D when standard methods fail.
- Alternative septal pacing via right ventricular leads can be effective for CRT-D in select patients.
- This strategy offers a potential solution for challenging left ventricular lead implantations.
Abstract:
Cardiac resynchronization therapy - defibrillator (CRT-D) is an effective treatment for ischemic heart failure (HF). But, it is a tricky challenge for left ventricular lead implantation difficulties during CRT-D. We report an ischemic cardiomyopathy patient with complete right bundle branch block (cRBBB) underwent CRT-D. During the implantation, the left anterior fascicular (LAF) region pacing was not ideal, and the implantation of left ventricular lead in lateral posterior or posterior wall was difficult. Then, leads were changed to be implanted into anterior septal region (near the LAF) and posterior septal region (near the LPF) from right ventricle, respectively. Synchronized pacing of LAB and LPB was performed to replace the pacing of left bundle branch region and left ventricular lateral posterior wall. Then, the QRS duration was shortened from 160ms to 100ms. During one month in follow-up, the patient's quality of life was good and the pacing parameters were stable. This case illustrates a technically feasible, hypothesis-generating bailout approach for selected patients when conventional coronary sinus left ventricular lead placement and standard conduction system pacing are unsuccessful.
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