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Management of Clostridioides difficile Infection in Patients with Inflammatory Bowel Disease
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, USA.
None:
Clostridioides difficile is a gram-positive, anaerobic bacteria that is ubiquitous. Oral-fecal transmission of the organism and its spores leads to C difficile colonization and infection (CDI) within the human gastrointestinal tract. Patients with inflammatory bowel disease (IBD) are more likely to be colonized with C difficile, develop CDI, and experience recurrence when compared to the general population. The biggest challenge of managing CDI in IBD remains diagnostic uncertainty and relies on clinicians' judgment.
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