Related Experiment Video
Updated: Aug 5, 2026
A Fluorescence-Based Method To Visualize Lipid Droplet And Organelle Dynamics During Mitosis in Hepatoma Cells
Published on: May 15, 2026
Cellular lipid imaging at the ultrastructural level
Fikadu G Tafesse1, Carsten Schultz2
1Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, OR, USA.
Abstract:
Lipids are fundamental organizers of biological membranes, yet visualizing lipid species within subcellular organelles has remained beyond experimental reach. Lennartz et al. introduce Lipid-correlative light and electron microscopy (CLEM), a CLEM workflow that maps lipid species onto membrane ultrastructure with nanoscale precision, uncovering active sphingomyelin sorting within the early endosome.
