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Published on: September 1, 2016
Normative Reference Values for Vibration, Warm and Cold Perception Thresholds in an Indian Population Using the
Srihari Sharma Kn1, Sunjyoth Hs1, Bhajish Bharathan2
1School of Health Sciences, College of Physiotherapy, Dayananda Sagar University, Bangalore South, Karnataka, India.
Annals of Neurosciences
|August 1, 2026
Summary
This study provides normative sensory threshold values for the Vibrasense + T device in healthy Indian adults. These age- and sex-stratified reference values aid in interpreting vibration, warm, and cold perception thresholds for clinical and research use.
Area of Science:
- Neurology
- Medical Devices
- Sensory Physiology
Background:
- Diabetic peripheral neuropathy is a significant diabetes complication, leading to foot ulcers and amputations.
- Quantitative sensory testing (QST) is crucial for assessing neuropathy.
- The Vibrasense + T device offers integrated testing of vibration, warm, and cold perception thresholds.
Purpose of the Study:
- To establish normative reference values for the Vibrasense + T device.
- To assess sensory thresholds in a healthy adult Indian population.
- To provide a baseline for clinical and research applications of the device.
Main Methods:
- A prospective cross-sectional study involving 345 healthy Indian adults (aged 18-93).
- Exclusion of individuals with diabetes, neuropathy, or other sensory-affecting conditions.
- Bilateral assessment of vibration perception threshold (VPT), warm perception threshold (WPT), and cold perception threshold (CPT) at hand and foot sites using the method of limits.
Main Results:
- Sensory thresholds were higher at the foot than the hand (p < .001).
- Age was associated with VPT and WPT, with thresholds increasing with age (p < .001).
- Females showed greater sensitivity than males; height, weight, and BMI had minimal impact.
Conclusions:
- Normative reference values for VPT, WPT, and CPT using Vibrasense + T were established for an Indian population.
- Age- and sex-stratified values are provided.
- These values will aid in the interpretation of sensory thresholds in clinical and research settings.
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