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Updated: Aug 5, 2026

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Published on: August 9, 2024
Virtual, Augmented, and Mixed Reality Technologies in Neurosurgical Training: Enhancing Skills and Surgical Outcomes:
Tayebeh Azarmehr1, Fatemeh Pouladkhay2, Jebraeil Farzi3
1Department of Operating Room, School of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, Iran.
Objective:
To systematically review the role of virtual reality (VR), augmented reality (AR), and mixed reality (MR) in neurosurgical education and training.
Design:
Systematic review conducted in accordance with the PRISMA guidelines.
Setting:
A comprehensive search was performed across PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar for English-language studies published between 1 January 2020 and 30 April 2026.
Participants:
Studies involving neurosurgeons, fellows, residents, and medical students (maximum sample size: n = 48) were included.
Results:
Of 7,204 initially identified studies, 25 met the inclusion criteria. VR was primarily used for surgical simulation (100% of VR studies) and anatomical education (62.5%). AR demonstrated broader applications, including preoperative planning (40%) and intraoperative support (30%). MR was evenly distributed across simulation, planning, and intraoperative support (40% each). The most frequently improved outcomes were training effectiveness (52%) and technical proficiency (44%). Methodological quality scores, assessed using the Modified Medical Education Research Study Quality Instrument (MMERSQI), ranged from 39.5 to 84.5, indicating varied rigor.
Conclusion:
VR, AR, and MR technologies show potential to enhance surgical precision, technical skills, and educational outcomes in neurosurgical training. However, standardization of methodologies and cost-effective solutions remain essential. Future research should focus on long-term clinical impact and integration of AI-driven training models.
