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Updated: Aug 5, 2026
Metabolic Pathway Confirmation and Discovery Through 13C-labeling of Proteinogenic Amino Acids
Published on: January 26, 2012
OpenMebius2: GUI-based software for 13C-metabolic flux analysis with tracer labeling pattern suggestions for precise
Tatsumi Imada1, Hiroshi Shimizu1, Yoshihiro Toya1
1Graduate School of Information Science and Technology, The University of Osaka, Yamadaoka 1-5, Suita, Osaka, Japan.
Abstract:
13C-metabolic flux analysis (¹³C-MFA) is a crucial technique that experimentally determines metabolic flux distribution. Although precision of each flux strongly depends on tracer labeling pattern, its optimization remains challenging. We developed an integrated platform, OpenMebius2, a graphical user interface (GUI)-based software for ¹³C-MFA that includes a tracer labeling pattern suggestion function to support subsequent experiments.
