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Updated: Aug 5, 2026

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Human Fear Conditioning Conducted in Full Immersion 3-Dimensional Virtual Reality
Published on: August 9, 2010
Virtual Reality as a Supportive Technology for Pediatric Intravenous Procedures: Effects on Fear and Autonomic
Pei-Shan Hsieh1, Hui-Ming Hou2, Chieh-Mao Chuang3
1Department of Intelligent Commerce, National Kaohsiung University of Science and Technology, Kaohsiung City, Taiwan.
Computers, Informatics, Nursing : CIN
|August 3, 2026
Summary
Virtual reality (VR) significantly reduced fear in children during intravenous procedures. While pain levels remained similar, VR showed potential as a supportive tool in pediatric nursing care.
Area of Science:
- Pediatric Nursing
- Medical Technology
- Psychophysiology
Background:
- Intravenous (IV) procedures in children often cause significant fear and discomfort.
- This distress can complicate procedure performance and patient experience.
- Supportive technologies are needed to mitigate fear during pediatric IV procedures.
Purpose of the Study:
- To investigate the efficacy of virtual reality (VR) as a supportive technology during pediatric IV procedures.
- To assess the impact of VR on children's fear and pain perception.
- To evaluate physiological responses, including autonomic nervous system activity, during IV procedures with VR.
Main Methods:
- A randomized, parallel-group study involving 50 children undergoing IV procedures.
- Participants were allocated to either a virtual reality group or a standard care comparison group.
- Fear and pain were measured via self-report; physiological data included heart rate variability, heart rate, and blood pressure.
Main Results:
- Children in the VR group reported significantly lower levels of fear compared to the control group.
- No significant differences in pain scores were observed between the VR and comparison groups.
- The VR group exhibited altered heart rate variability indices, indicating a less dominant sympathetic autonomic response, correlating with reduced fear.
Conclusions:
- Virtual reality demonstrates potential as an effective supportive technology for reducing fear in children during IV procedures.
- VR may offer clinical benefits in pediatric nursing by improving patient comfort and cooperation.
- Further research into VR's psychophysiological effects can optimize its application in healthcare settings.