Multifocal Oral Epithelial Hyperplasia Associated With Papillomavirus Infection in a Road Killed Brown Howler Monkey
Sandy Lorena Pulecio-Santos1, Vivian Renata Kida1, Alex Junior Souza de Souza1
1Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo (USP), São Paulo, Brazil.
Journal of Medical Primatology
|August 4, 2026
Abstract:
A free-ranging road-killed brown howler monkey (Alouatta guariba clamitans) presented multiple mucosal-colored papules and plaques on oral mucosa. Pathological evaluation confirmed the diagnosis of epithelial hyperplasia with koilocytosis. Papillomavirus antigens were demonstrated by immunohistochemistry, and PCR was positive for partial amplification of Alouatta guariba papillomavirus 1 DNA.
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