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Oral Carcinoma Cuniculatum: Diagnostic Challenges and Emerging Perspectives-Case Report
Toniya Raut1, Neetu Jain1, Shashi Keshwar1
1Department of Oral Pathology, College of Dental Surgery, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
Cancer Reports (Hoboken, N.J.)
|August 4, 2026
Summary
Oral carcinoma cuniculatum (OCC), a rare squamous cell carcinoma, is often misdiagnosed due to its subtle features and burrowing pattern. Early recognition and consideration in differential diagnosis are crucial for accurate patient management.
Area of Science:
- Oral pathology
- Oncology
- Surgical pathology
Background:
- Oral carcinoma cuniculatum (OCC) is a rare, locally aggressive squamous cell carcinoma (SCC).
- Characterized by a burrowing lesion and osteolytic defect, it often lacks obvious cytological atypia.
- Rarity and distinct pattern lead to frequent misdiagnosis or underdiagnosis on incisional biopsy.
