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Updated: Aug 5, 2026

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Direct 15N-13C Heteronuclear Correlation Spectroscopy Enhanced by Spin-Lock-Induced Crossing and Reversible

Danil A Markelov1,2, Alexey S Kiryutin1, Nikita V Chukanov1

  • 1International Tomography Center, Siberian Branch of the Russian Academy of Science, Institutskaya 3A, Novosibirsk630090, Russia.

The Journal of Physical Chemistry Letters
|August 4, 2026
PubMed
Summary

This study introduces Signal Amplification By Reversible Exchange (SABRE) hyperpolarization for enhanced Nuclear Magnetic Resonance (NMR) spectroscopy. This method significantly improves sensitivity for 15N-13C heteronuclear correlation, enabling faster, site-specific analysis of small molecules.

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