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Large language model-based simulated patient training for heart failure palliative care communication: a pilot study
Risa Kishikawa1, Hiroyuki Morita1,2, Satoshi Kodera1
1Department of Cardiovascular Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
European Heart Journal. Digital Health
|August 5, 2026
Summary
This study explored a web-based large language model (LLM) for training heart failure palliative care communication. The LLM application proved feasible and showed early improvements in physician self-efficacy for difficult conversations.
Area of Science:
- Medical Education
- Artificial Intelligence in Healthcare
- Palliative Care
Background:
- Effective communication in heart failure (HF) palliative care is crucial but challenging to train at scale.
- Traditional training methods like role-playing require significant resources (facilitators, standardized patients).
- Large language models (LLMs) offer a potential solution for scalable communication skills development.
Purpose of the Study:
- To evaluate the feasibility of a web-based LLM-driven communication training application for HF palliative care.
- To assess the early educational impact of the LLM on physicians' self-efficacy in conducting these sensitive conversations.
Main Methods:
- A single-arm pilot study involving physicians using a Japanese-language LLM application simulating advanced HF patients.
- Automated, framework-based feedback was provided by the LLM.
- Physician self-efficacy was measured using pre- and post-session questionnaires.
Main Results:
- Ten sessions were analyzed, with physicians engaging in an average of 7.6 dialogue turns.
- Significant improvements were noted in knowledge of palliative care communication (adjusted P < 0.01) and confidence in HF palliative care communication (adjusted P = 0.03).
- LLM response and feedback generation times were rapid (approx. 3s and 17s, respectively).
Conclusions:
- A web-based LLM-simulated patient system is feasible for training HF palliative care communication.
- The LLM demonstrated an early positive educational signal on physician self-efficacy.
- LLM-driven training may supplement traditional methods, warranting further investigation in larger controlled studies.
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