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Updated: Aug 7, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Nontuberculous Mycobacterial Skin and Soft Tissue Infections
Hanna Matthews1, Kevin L Winthrop2
1Section of Infectious Diseases, University Hospital Hamburg-Eppendorf, Hamburg, Germany; Division of Infectious Diseases, Oregon Health and Science University, Portland, OR, USA.
Abstract:
Mycobacterial skin and soft tissue infections (SSTIs) represent a diagnostically challenging and heterogeneous group of diseases caused by nontuberculous mycobacteria (NTM), M tuberculosis complex, and M leprae. This review will focus on SSTIs caused by NTM. Rapidly growing mycobacteria predominate in iatrogenic and health care-associated infections, while M marinum and M ulcerans are linked to aquatic exposure. Diagnostic delay remains a universal challenge due to nonspecific presentations and the need for specialized laboratory techniques. Treatment requires pathogen-specific combination regimens. This review summarizes the epidemiology, clinical manifestations, diagnostic approach, and treatment strategies of mycobacterial SSTIs, with emphasis on NTM.
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