Related Experiment Video
Updated: Aug 7, 2026

07:14
Virtual Agent for Real-Time Motivational Interviewing by Integrating Adaptive Nonverbal Behavior and Language Models
Published on: December 23, 2025
A Conversational Ethics Bot (CALEB) Versus GPT-4o for Medical Ethics Education: Transcript Analysis and Extended
Rohan Jotwani1, Vansh D Barot2, Peter A Goldstein1,3,4
1Department of Anesthesiology, Weill Cornell Medicine, New York, NY, USA.
Journal of Medical Extended Reality
|August 6, 2026
Summary
A new conversational agent, CALEB (Conversational Agent Learning Ethics Bot), offers a distinct approach to medical ethics education. It uses extended reality (XR) for immersive, case-based moral deliberation, showing higher empathy than general AI.
Area of Science:
- Medical Education
- Artificial Intelligence
- Ethics
Background:
- Medical ethics education struggles with standardization and often relies on didactic methods.
- Current large language models (LLMs) lack embodied, conversational engagement for realistic ethics discussions.
Purpose of the Study:
- To develop and evaluate CALEB (Conversational Agent Learning Ethics Bot), an XR-enabled agent for pragmatic, case-based medical ethics deliberation.
- To compare CALEB's pedagogical distinctiveness against general-purpose LLMs like GPT-4o.
Main Methods:
- CALEB integrates a medical ethics knowledge base, persona design, and bounded generative architecture.
- A two-phase feasibility study compared CALEB and GPT-4o via transcripts and live XR interaction with medical ethicists.
Main Results:
- GPT-4o produced longer, comprehensive responses; CALEB generated shorter, principle-dense responses with first-person and emotional language.
- CALEB demonstrated significantly higher empathy scores (p < 0.001) in interpretive dimensions.
- Live XR interaction favored CALEB's perceived effectiveness over transcript-only review.
Conclusions:
- Domain-specific agents like CALEB are feasible and offer a distinct pedagogical approach compared to general LLMs.
- Specialized and foundational AI systems may complement each other in scalable medical ethics training.
Related Concept Videos
Ethics and Bioethics
Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...
Ethical Dilemmas II
Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
Ethics in Research
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
Ethical Dilemmas I
Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
Ethical Issues
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
Ethical Concerns in Healthcare:
Nursing Ethical Principles II
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
