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A Cross-sectional Study Comparing Pulmonary Function and Exercise Capacity in Posttuberculosis Sequelae Patients
1Department of Respiratory Medicine, Shri Sathya Sai Medical College and Research Institute, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, India.
Annals of African Medicine
|August 6, 2026
Summary
Smoking significantly worsens respiratory health in tuberculosis survivors, leading to reduced lung function and exercise capacity. Quitting smoking and pulmonary rehabilitation are crucial for managing long-term respiratory impairment after TB.
Area of Science:
- Pulmonology
- Respiratory Medicine
- Public Health
Background:
- Post-tuberculosis (TB) lung disease causes significant long-term respiratory morbidity.
- The impact of smoking on pulmonary function and exercise capacity in TB survivors is not well-established.
- Limited comparative data exists between smokers and nonsmokers with post-TB sequelae.
Purpose of the Study:
- To evaluate and compare pulmonary function in post-TB patients.
- To assess and compare exercise capacity in post-TB patients.
- To investigate the differential effects of smoking versus nonsmoking in TB sequelae.
Main Methods:
- Cross-sectional study involving 110 post-TB patients (55 smokers, 55 nonsmokers).
- Pulmonary function assessed via spirometry (FEV1, FVC, FEV1/FVC, PEFR).
- Exercise capacity evaluated using the 6-min walk test and Modified Borg Dyspnea Scale.
Main Results:
- Smokers exhibited significantly lower FEV1, FVC, FEV1/FVC ratio, and PEFR compared to nonsmokers.
- Obstructive ventilatory defects were more prevalent in smokers.
- Smokers had a reduced 6-min walk distance and higher Borg dyspnea scores.
Conclusions:
- Smoking exacerbates pulmonary impairment and reduces exercise capacity in individuals with post-TB sequelae.
- Smoking acts as an additive risk factor for chronic respiratory issues in TB survivors.
- Integrating smoking cessation and pulmonary rehabilitation is vital for post-TB care.
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