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Updated: Aug 8, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
11:37

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

2'-O-Acetal Levulinic Ester Ribonucleoside 3'-Phosphoramidites for the Solid-Phase Synthesis of Long RNA

Zidi Lyu1, Adam Katolik1, Masad J Damha1

  • 1Department of Chemistry, McGill University, Montreal, Canada.

Current Protocols
|August 6, 2026
PubMed
Abstract

Keywords:
2' acetal levulinic esterRNA solid‐phase synthesisfast RNA deprotectionlong synthetic RNAreverse‐phase HPLCriboswitchsingle guide RNA

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