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Updated: Aug 8, 2026

Finite Element Modelling of a Cellular Electric Microenvironment
Published on: May 18, 2021
Effect of a 3-D cell membrane model combined with an interactive online platform on health students' learning of
Ana Carolina Souza da Rosa1, Giulia Azevedo Martinez1, Anna Cecília Perretto Vieira de Souza1
1Physiology Research Group, Stress, Memory and Behavior Lab, Federal University of Pampa, Uruguaiana, Rio Grande do Sul, Brazil.
Abstract:
Understanding cellular physiology, particularly transport across the plasma membrane, remains a significant challenge for undergraduate health sciences students, as these microscopic processes are inherently difficult to visualize. Innovative teaching strategies, such as three-dimensional (3-D) models, may enhance students' comprehension of these concepts. This study investigated the impact of a 3-D cell membrane puzzle model combined with an interactive online platform on learning about membrane transport. Undergraduate nursing and physical therapy students participated in the activity during a practical class, and learning outcomes were assessed with pre- and posttests, as well as subjective evaluations. The results demonstrated an improvement in students' self-perceived knowledge of the main mechanisms of membrane transport and highlighted the importance of assessing students' knowledge in addition to self-perception. These findings suggest that playful and interactive tools can effectively support the teaching and learning of complex physiological concepts.NEW & NOTEWORTHY Cell membranes are invisible to the naked eye, yet vital to life. For health care students, understanding transport across membranes can be challenging. This study combined a 3-D puzzle model with an online platform to make these processes tangible and easier to grasp. Students who used this interactive approach improved their self-perception of cellular function, showing that playful, hands-on educational strategies can facilitate learning of complex biological concepts and promote greater engagement in the learning process.
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