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Updated: Aug 8, 2026

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Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
Machine learning surrogate forward models for biomechanical laryngeal control
Jesús A Parra1, Clara Sorolla1, Nicolás F Quinteros1,2
1Advanced Center for Electrical and Electronic Engineering, Universidad Técnica Federico Santa María, Valparaíso, Chile.
The Journal of the Acoustical Society of America
|August 7, 2026
Summary
Machine learning models offer fast, accurate alternatives to traditional biomechanical models for voice production. These surrogates enable real-time laryngeal motor control, crucial for understanding voice disorders.
Area of Science:
- Computational biophysics
- Voice production mechanisms
- Machine learning applications
Background:
- Accurate laryngeal motor control modeling is vital for voice production research.
- Traditional biomechanical models are computationally intensive for real-time applications.
- Need for efficient alternatives to direct numerical simulation.
Purpose of the Study:
- Evaluate machine learning (ML) regressors as surrogate forward models for laryngeal motor control.
- Compare random forest (RF), neural networks (NN), and polynomial regression (PR) performance.
- Assess ML surrogates for real-time voice tracking and subject-specific modeling.
Main Methods:
- Generated training data using extended and triangular body-cover vocal fold models.
- Trained RF, NN, and PR models to map laryngeal inputs to fundamental frequency and sound pressure level.
- Evaluated inference speed, accuracy, control signal smoothness, and memory footprint.
Main Results:
- ML surrogates achieved millisecond-scale inference (e.g., 2ms for PR), enabling real-time tracking.
- RF offered highest accuracy; NN and PR provided smoother control and smaller memory usage.
- Performance degraded significantly below ~1000 training samples.
Conclusions:
- ML surrogates are efficient, adaptable alternatives to direct numerical simulation for laryngeal modeling.
- These models facilitate real-time inverse Jacobian control and hold potential for subject-specific modeling via transfer learning.
- Identified a practical training data threshold for reliable ML model performance.

