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Updated: Aug 9, 2026

Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase
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Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase

Published on: June 30, 2023

CircHECTD1 Promotes Cholangiocarcinoma Progression Through Interaction With SFPQ to Induce Autophagy

Shouwen Zhao1, Shanshan Jiang1, Xutong Wang2

  • 1Department of Hepatobiliary Surgery, Xingtai People's Hospital, Xingtai, China.

Cancer Science
|August 8, 2026
PubMed
Summary

Circular RNAs (circRNAs) like circHECTD1 promote cholangiocarcinoma (CCA) growth by enhancing autophagy. This involves circHECTD1 interacting with SFPQ to boost ATG12 expression and promote tumor progression.

Keywords:
ATG12 transcriptionCCA progressionSFPQcell autophagycircHECTD1

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