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Updated: Aug 9, 2026
03:57
Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
Published on: July 14, 2023
Audiovestibular Outcomes After Parathyroidectomy in Primary Hyperparathyroidism
Erdem Köroğlu1, Halil Erdem Özel1, Seda Erem Basmaz2
1Department of Otorhinolaryngology-Head and Neck Surgery, Kocaeli City Hospital University of Health Sciences Kocaeli Türkiye.
Laryngoscope Investigative Otolaryngology
|August 8, 2026
Summary
Parathyroidectomy significantly improved dizziness and related disability in primary hyperparathyroidism (pHPT) patients. Objective audiological and vestibular tests showed minimal changes, suggesting metabolic correction impacts symptom perception.
Area of Science:
- Otolaryngology
- Endocrinology
- Neurosurgery
Background:
- Primary hyperparathyroidism (pHPT) is a common endocrine disorder.
- Vestibular dysfunction can manifest in patients with pHPT.
- The impact of parathyroidectomy on audiovestibular function requires further investigation.
Purpose of the Study:
- To prospectively evaluate audiovestibular outcomes after parathyroidectomy in pHPT patients.
- To assess changes in audiological, vestibular, and patient-reported outcomes.
- To determine the effect of metabolic correction on dizziness and vestibular symptoms.
Main Methods:
- Prospective observational study of 31 adult pHPT patients undergoing parathyroidectomy.
- Comprehensive audiological (audiometry) and vestibular assessments (vHIT, VNG, SVV, VDI) pre- and post-surgery.
- Primary outcome: change in Vestibular Disability Index (VDI) score.
Main Results:
- Hearing thresholds and most vestibular function tests remained stable post-surgery.
- Significant improvement in VDI scores, indicating reduced dizziness-related disability (p=0.001).
- Some statistically significant but clinically minor changes observed in specific vHIT canal gains and asymmetries.
Conclusions:
- Parathyroidectomy significantly improves subjective vestibular symptoms and reduces dizziness disability in pHPT patients.
- Metabolic correction may enhance vestibular symptom perception beyond objective test capabilities.
- Further research with larger cohorts and longer follow-up is warranted.
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