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Updated: Aug 11, 2026

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Minimally Invasive Surgical Decompression of Occipital Nerves
Published on: September 13, 2024
Endoscopic Endonasal Optic Nerve Decompression for Traumatic Optic Neuropathy: A Systematic Review
Babak Ganjeifar1, Seyed Reza Ahmadi Koupaei2, Ali Moradi3,4
1Department of Neurosurgery, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Romanian Journal of Ophthalmology
|August 10, 2026
Summary
Endoscopic optic nerve decompression (EOND) effectively treats traumatic optic neuropathy (TON), restoring vision in 58.4% of patients unresponsive to steroids. This minimally invasive surgery shows promise, though further research is needed.
Area of Science:
- Neurosurgery
- Ophthalmology
- Minimally Invasive Surgery
Background:
- Traumatic optic neuropathy (TON) is an optic nerve injury causing vision loss.
- Endoscopic transsphenoidal optic nerve decompression (EOND) is a minimally invasive surgical approach.
Purpose of the Study:
- To systematically review the efficacy and safety of EOND for TON.
- To evaluate visual outcomes and complication rates associated with EOND in TON patients.
Main Methods:
- Systematic literature search of PubMed, Scopus, and Google Scholar (2014-2024).
- Inclusion of 16 studies analyzing EOND for TON.
- Analysis of visual recovery rates and postoperative complications.
Main Results:
- Mean visual recovery rate of 58.4% in TON patients treated with EOND.
- Postoperative complications occurred in 25% of studies, primarily cerebrospinal fluid (CSF) leaks.
- EOND demonstrated advantages in invasiveness and visualization compared to traditional methods.
Conclusions:
- EOND is a safe and effective treatment for TON patients unresponsive to steroids.
- Further high-quality research and standardized protocols are needed to optimize EOND outcomes.
- Minimally invasive nature and improved visualization are key benefits of EOND.
Keywords:
CT = Computed tomographyEOND = Endoscopic optic nerve decompressionMRI = Magnetic resonance imagingOND = Optic nerve decompressionRAPD = Relative afferent pupillary defectRGC = Retinal ganglion cellsTON = Traumatic optic neuropathyVA = Visual acuityendoscopic surgeryminimally invasiveoptic nerve decompressionoptic nerve injurytranssphenoidal surgerytraumatic optic neuropathyvisual recovery