Erratum

Area of Science:

• Immunology
• Hepatology
• Pharmacovigilance

Background:

• The article "Global Estimates of Vaccine-Associated Hepatic Autoimmune Disorders and Their Related Vaccines, 1968-2024" by Jeong et al. has undergone corrections.
• Corrections were made following communication with the Uppsala Monitoring Centre (WHO Collaborating Centre for International Drug Monitoring) regarding dataset accuracy and data use policies.

Purpose of the Study:

• To update and ensure the accuracy of the reported global estimates of vaccine-associated hepatic autoimmune disorders.
• To clarify the methodology and data sources used in the analysis of the WHO Pharmacovigilance Database.

Main Methods:

• The Vigibase database size was corrected from "over 140 million cases" to "over 35 million cases."
• Ethical approval statement was clarified to reflect IRB approval from Kyung Hee University Medical Center and data access from the Uppsala Monitoring Centre.
• The study utilized disproportionality analysis on spontaneous adverse event reports, not for estimating incidence or prevalence.

Main Results:

• The authors confirm that the corrections do not alter the main results, interpretations, or conclusions of the original study.
• The terminology 'vaccine-associated' was clarified to indicate signal detection through disproportionality analysis, not implying causality.

Conclusions:

• Findings regarding vaccine-associated hepatic autoimmune disorders should be interpreted with caution due to the nature of spontaneous reporting data.
• The study emphasizes that the terminology used does not imply causality or serve as a basis for clinical decision-making.