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In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Hereditary Renal Cell Carcinoma: An Imaging Update
Mindy X Wang1, Mahmoud Diab2, Albert R Klekers1
1Department of Abdominal Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1473, Houston, TX 77030, USA.
Abstract:
Hereditary renal cancer syndromes are rare, yet contribute to early-onset renal cell carcinoma (RCC) and require vigilant imaging surveillance. These syndromes, including Von Hippel-Lindau, Birt-Hogg-Dubé, hereditary papillary RCC, are linked to germline mutations affecting tumor suppressor pathways. Imaging techniques, such as MR imaging and computed tomography, play a crucial role in early diagnosis, characterization, and surveillance of hereditary RCC. A multidisciplinary approach is essential for individualized screening and management strategies. This review highlights the genetic associations, imaging features, and most up-to-date recommendations for screening and surveillance of hereditary RCC syndromes.
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