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Evidence-Based Nursing Management of Semi-Implantable Intrathecal Drug Delivery Systems for Refractory Cancer Pain:
Xu-Ling Pan1, Xiao-Mei Song2, Xiao-Xia Wang1
1Department of Pain, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Nursing & Health Sciences
|August 12, 2026
Summary
A new evidence-based nursing protocol for implantable drug delivery systems (IDDS) significantly improved refractory cancer pain management. This standardized approach led to better pain relief, fewer adverse events, and increased patient satisfaction.
Area of Science:
- Oncology Nursing
- Pain Management
- Evidence-Based Practice
Background:
- Refractory cancer pain poses a significant challenge in patient care.
- Standardized nursing protocols are crucial for effective management of complex treatments like semi-implantable implantable drug delivery systems (IDDS).
Purpose of the Study:
- To develop and evaluate an evidence-based nursing protocol for semi-implantable IDDS in patients with refractory cancer pain.
- To standardize perioperative nursing care and improve clinical outcomes.
Main Methods:
- Utilized the Joanna Briggs Institute (JBI) evidence translation model to synthesize 34 best-evidence statements (2015-2025).
- Developed a perioperative nursing protocol for semi-implantable IDDS.
- Implemented the protocol in 32 patients and compared outcomes to 31 pre-implementation patients.
Main Results:
- The evidence-based protocol significantly improved pain relief rates and patient satisfaction (p < 0.05).
- Overall adverse events, including infections, were reduced (p < 0.05).
- Compliance with nursing quality indicators, especially home care education, improved significantly (p < 0.001), alongside enhanced nursing staff knowledge and performance.
Conclusions:
- The developed evidence-based nursing protocol for semi-implantable IDDS is effective in managing refractory cancer pain.
- Implementation is associated with better pain control, reduced device-related adverse events, and higher patient satisfaction.
- The protocol demonstrates feasibility for wider clinical adoption.
