Common and Uncommon Splenic Lesions: A Review

Background/Objectives: Briefly review the imaging and pathologic findings associated with common and uncommon splenic lesions. These lesions are often incidental and cause a diagnostic dilemma in determining the need for further work-up and follow-up. Methods/Results: A step-by-step review of splenic lesions will be provided. This includes general demographics, fundamental pathology, and key imaging features. Conclusions: Splenic lesions are often challenging due to their relatively uncommon presentation, predominantly incidental detection, and broad age of incidence. The vast majority of these lesions, however, are benign. Correlation with the patient demographics and specific elements of the patient history will often significantly narrow the differential diagnosis.