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Common and Uncommon Splenic Lesions: A Review
Rajvir Teja1, Evan Allarie2, Christopher Fung2
1Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2B7, Canada.
Diagnostics (Basel, Switzerland)
|August 13, 2026
Summary
This review covers imaging and pathology of splenic lesions, often found incidentally. Most splenic lesions are benign, and patient history aids diagnosis.
Area of Science:
- Radiology
- Pathology
- Gastroenterology
Background:
- Splenic lesions are frequently incidental findings.
- They present a diagnostic challenge for further management.
- Understanding imaging and pathology is crucial.
Purpose of the Study:
- To review imaging and pathologic findings of splenic lesions.
- To aid in differentiating benign from potentially malignant conditions.
- To guide further work-up and follow-up decisions.
Main Methods:
- Systematic review of splenic lesions.
- Analysis of general demographics.
- Evaluation of fundamental pathology and key imaging features.
Main Results:
- Splenic lesions exhibit diverse presentations across age groups.
- Incidental detection is common.
- The majority of splenic lesions are benign.
Conclusions:
- Splenic lesions pose diagnostic challenges due to uncommon presentation and incidental detection.
- Patient demographics and history significantly aid in narrowing differential diagnoses.
- Most splenic lesions are benign, reducing the need for aggressive intervention.