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Updated: Aug 14, 2026
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Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
Published on: August 31, 2019
Edible Fungal Polysaccharide-Liposome: Interfacial Interactions, Structure-Function Relationship, and Emerging
Jiachen Liang1, Abdul Mueed1, Abdul Basit2
1School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
International Journal of Molecular Sciences
|August 13, 2026
Summary
Edible fungal polysaccharides (EFPs) enhance liposome delivery systems for improved stability and bioavailability. This review explores EFP-liposome interactions, applications, and identifies key research gaps for future development.
Area of Science:
- Nanotechnology
- Biomaterials Science
- Food Science
Background:
- Liposomes offer excellent biocompatibility and delivery capabilities for bioactive compounds.
- Edible fungal polysaccharides (EFPs) possess valuable antioxidant and immunomodulatory properties.
- Combining EFPs with liposomes creates advanced nanocarriers with improved stability and function.
Purpose of the Study:
- To provide a comprehensive review of edible fungal polysaccharide-liposome (EFP) systems.
- To elucidate the interactions between EFPs and lipid bilayers.
- To critically evaluate the applications and identify research gaps in EFP-liposome technology.
Main Methods:
- Literature review focusing on EFP-liposome interfacial interactions.
- Analysis of EFP effects on liposomal properties and biological performance.
- Evaluation of emerging applications and future research directions.
Main Results:
- EFPs interact with lipid bilayers via hydrogen bonding, electrostatic, and hydrophobic interactions.
- EFPs enhance liposomal stability, encapsulation, mucoadhesion, and cellular uptake.
- EFP-liposomes show promise in targeted delivery, oral delivery, and gut microbiota modulation.
Conclusions:
- EFP-liposome systems offer a promising platform for developing multifunctional nanocarriers.
- Understanding structure-function relationships and biological transport is crucial for optimization.
- Further research is needed to address manufacturing challenges and fully realize translational applications.
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