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Transitioning AI-based sperm assessment from proof-of-concept to clinical practice

Erica T Y Leung1, Xianghan Mei2, Brayden K M Lee1

  • 1Department of Obstetrics and Gynaecology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

Human Reproduction Open
|August 13, 2026
PubMed
Abstract

No abstract available in PubMed .

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Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...