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Updated: Aug 15, 2026
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Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma
Published on: January 12, 2024
Presumed Secondary Vitreoretinal Lymphoma with Response to Systemic Therapy Alone: Case Report
Alyssa C Huelsbeck1, Colin P Froines2, Julie E Chang3
1University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Case Reports in Ophthalmology
|August 14, 2026
Summary
Secondary vitreoretinal lymphoma (VRL) in a diffuse large B-cell lymphoma patient responded well to systemic chemotherapy alone. Multimodal imaging confirmed lesion resolution without the need for intravitreal treatment or biopsy.
Area of Science:
- Ophthalmology
- Oncology
- Medical Imaging
Background:
- Intraocular lymphoma, specifically vitreoretinal lymphoma (VRL), is a rare malignancy.
- There is currently no standard treatment regimen for intraocular lymphoma.
- Secondary VRL can present as subretinal involvement, impacting visual acuity.