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Updated: Aug 16, 2026

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
15:48

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies

Published on: July 29, 2007

LSD therapy: A few hundred meters from where it began

Felix Müller1, Anna M Becker1, Christopher Böhlke2

  • 1University of Basel, Department of Psychiatry (UPK), 4012 Basel, Switzerland; University Hospital Basel and University of Basel, Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, 4031 Basel, Switzerland.

Med (New York, N.Y.)
|August 14, 2026
PubMed
Abstract

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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