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Updated: Aug 16, 2026

Directed Differentiation of Induced Pluripotent Stem Cells towards T Lymphocytes
12:47

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Published on: May 14, 2012

In situ programming of unconventional T cells

Yan-Ruide Li1, Haochen Nan2, Youcheng Yang2

  • 1Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Trends in Biotechnology
|August 14, 2026
PubMed
Summary

Unconventional T cells (UTCs) show promise for immunotherapy but face challenges in solid tumors. Biomaterials offer a way to program these cells in situ, improving cancer treatment efficacy and safety.

Keywords:
MAIT cellsNKT cellsUTCsbiomaterial-based deliveryin situ immunoengineeringγδ T cells

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