Cervical Myofibroblastoma: Expanding the Differential for Cervical Masses

Area of Science:

• Gynecologic Oncology
• Pathology
• Oncology

Background:

• Lower genital tract myofibroblastomas are exceptionally rare gynecologic neoplasms.
• Published literature primarily comprises case reports, highlighting diagnostic challenges and rarity.
• Differential diagnoses include cervical leiomyomas, nabothian cysts, and angiomyofibroblastomas.

Purpose of the Study:

• To report a rare case of cervical myofibroblastoma in a 32-year-old female.
• To contribute to the limited body of literature on this rare gynecologic tumor.
• To review and compare with previously reported cases of cervical myofibroblastoma.

Main Methods:

• Surgical excision of a large cervical lesion.
• Histopathological examination of the excised tissue.
• Comprehensive literature review of cervical myofibroblastoma cases since 2017.

Main Results:

• A 32-year-old female presented with and was diagnosed with cervical myofibroblastoma post-excision.
• This represents the sixth reported case of cervical myofibroblastoma since 2017.
• The case adds to the understanding of the clinical presentation and pathology of this rare tumor.

Conclusions:

• Cervical myofibroblastoma is a rare entity requiring careful differential diagnosis.
• Further research is needed to elucidate the pathogenesis, potentially involving hormonal or infectious factors.
• This case underscores the importance of reporting rare gynecologic neoplasms to expand medical knowledge.