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Mesenteric and Retroperitoneal Mucinous Cystic Neoplasms: A Nongynecologic Process Commonly Managed by Gynecologic
Judy Hayek1, Jennifer Wolf1, Alexandra Hamilton2
1Division of Gynecologic Oncology, Maimonides/SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Case Reports in Obstetrics and Gynecology
|March 4, 2026
Summary
Retroperitoneal mucinous cystic neoplasms are rare. This case series suggests a potential link between diverticular disease and these rare neoplasms, highlighting unique patient presentations and complications.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Retroperitoneal mucinous cystic neoplasms (RMCNs) are rare, with limited data on diagnosis and treatment.
- Existing knowledge is primarily based on isolated case reports and small case series.
Purpose of the Study:
- To describe a case series of two patients with mesenteric-retroperitoneal mucinous cystic neoplasms.
- To investigate a potential correlation between diverticular disease and the histopathology of RMCNs.
Main Methods:
- Surgical resection of pelvic masses suspicious for adnexal neoplasms.
- Pathological examination of surgical specimens.
- Review of patient histories for comorbidities, specifically diverticular disease.
Main Results:
- Two patients presented with pelvic masses; pathology revealed mesenteric-retroperitoneal mucinous cystic neoplasms.
- Both patients had a history of diverticulosis.
- Both patients experienced perioperative complications related to diverticulitis.
Conclusions:
- Mesenteric-retroperitoneal mucinous cystic neoplasms can present as pelvic masses.
- A possible association between diverticular disease and RMCNs warrants further investigation.
- Complications such as diverticulitis may occur during the perioperative management of these patients.
