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Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor
Published on: May 2, 2022
Multitarget Molecular Imaging-based Characterization of Gastrointestinal Stromal Tumor
Sayan Manna1,2, Saurabh Jindal1, Farrokh Dehdashti1,3
1Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO.
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The imaging arsenal for nuclear medicine physicians continues to grow rapidly with multiple radiopharmaceuticals now being used routinely in clinical practice. More specifically, PET imaging targeting various aspects of tumor biology has demonstrated utility in diagnosing incidental/synchronous malignancies as well as biochemical profiling of tumors for prognostication (ie, in the setting of prostate and neuro-endocrine cancers). These concepts are illustrated in this case of an incidental gastric gastrointestinal stromal tumor (GIST) which was imaged with 3 separate PET radiopharmaceuticals.
