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Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach
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Designing time-limited aryl hydrocarbon receptor drugs: A kinetic framework from the FICZ-CYP1A1 feedback axis

Mahmoud Omidi1, Amir Shadboorestan2, Afshin Mohammadi-Bardbori3

  • 1Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Drug Discovery Today
|August 19, 2026
PubMed

Keywords:
6-formylindolo[3,2-b]carbazole (FICZ)aryl hydrocarbon receptor (AHR)cytochrome P450 1A1 (CYP1A1)kinetic pharmacologypro-drugsignal durationtapinarof

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