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Updated: Aug 21, 2026
Manual Segmentation of the Human Choroid Plexus Using Brain MRI
Published on: December 15, 2023
Automatic MRI-Based segmentation of ablation zones in spine and liver: A comparative study of network performance and
Janine Rothert1,2,3, Sylvia Saalfeld4, Marcel Gutberlet5,6
1Institute for Medical Engineering, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany. janine.rothert@ovgu.de.
Purpose:
Ablation therapies are a treatment option for cancer patients, particularly for conditions such as spinal metastases and liver tumors. Precisely delineating ablation zones is essential for accurately assessing treatment success. However, research in MRI-guided interventions remains limited for automated segmentation approaches and quantitative analysis.
Methods:
We developed a framework for automated segmentation of ablation zones following thermal interventions. The performance was tested on two representative types of clinical cases from different clinical sites: post-ablative liver lesions and spinal metastases. Four leading neural networks (nnUNet, TransUNet, SwinUNETR, and SwinUNETR-V2) were evaluated for their segmentation accuracy in segmenting necrotic tissue. Additionally, a statistical analysis was performed to investigate the influence of an optimized image ROI selection on the segmentation performance.
Results:
The nnUNet achieved the highest segmentation performance, with a Dice Similarity Coefficient of 83.3 ± 13.2% for spinal metastases and 82.2 ± 12.4% for liver lesions. The statistical analysis revealed that cropping images to a standardized ROI size provided the optimal balance between user interaction and networks' performance.
Conclusion:
The automated segmentation accuracies are comparable to the inter-rater variability observed among radiologists for spinal imaging and establish the new state-of-the-art for liver MRIs, indicating the potential to facilitate the clinical routine for interventions.
