A review on tumor-targeting liposomes: Fabrication, mechanism and applications

Liposome-mediated targeted drug delivery represents a groundbreaking advancement in oncology, significantly enhancing therapeutic efficacy and safety. This review explores the versatility of liposomal systems in efficiently encapsulating and precisely delivering drugs to tumor tissues, thereby minimizing systemic toxicity and improving treatment specificity. Liposome-based technologies hold great potential to revolutionize cancer therapy by overcoming multidrug resistance and enabling tumor-specific targeting. The study underscores the critical need for continued research focused on deepening mechanistic insights, advancing formulation strategies, and conducting rigorous clinical validation. Future directions emphasize the promise of personalized precision medicine, leveraging liposomes to tailor therapies based on individual patient profiles and tumor characteristics. These innovations not only aim to boost therapeutic outcomes but also reduce adverse effects, ultimately improving patient quality of life. In conclusion, liposome-mediated drug delivery stands at the forefront of cancer treatment innovation, with ongoing research essential to translating these advances into clinical success and offering renewed hope to cancer patients worldwide.