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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
10:10

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Hypercalcemia in active pulmonary tuberculosis.

A A Abbasi, J K Chemplavil, S Farah

    Annals of Internal Medicine
    |March 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Active pulmonary tuberculosis patients taking vitamin D supplements may develop hypercalcemia. This condition, characterized by elevated serum calcium, often resolves spontaneously but requires further investigation into its exact mechanism.

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    09:34

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    Area of Science:

    • Endocrinology
    • Pulmonology
    • Infectious Diseases

    Background:

    • Hypercalcemia is a potential complication in various medical conditions.
    • The interplay between tuberculosis, vitamin D, and calcium metabolism requires further elucidation.

    Purpose of the Study:

    • To determine the incidence of hypercalcemia in patients with active pulmonary tuberculosis.
    • To investigate the relationship between vitamin D intake and hypercalcemia in tuberculosis patients.

    Main Methods:

    • Prospective study comparing 79 tuberculosis patients with 79 chronic obstructive pulmonary disease patients.
    • Monitoring serum calcium levels and daily vitamin D intake over 4 to 16 weeks.
    • Correlation analysis between vitamin D dosage and hypercalcemia parameters.

    Main Results:

    • Twenty-two (28%) tuberculosis patients developed hypercalcemia (serum calcium > 10.5 mg/dl).
    • Hypercalcemia duration ranged from 1 to 7 months, with spontaneous remission in all cases.
    • Higher daily vitamin D intake correlated positively with hypercalcemia degree and duration.

    Conclusions:

    • Active pulmonary tuberculosis is associated with an increased risk of hypercalcemia, particularly with vitamin D supplementation.
    • Vitamin D intake appears to be a significant factor in the development of hypercalcemia in this population.
    • The precise mechanism linking tuberculosis activity, vitamin D, and hypercalcemia remains undetermined.