Multimodal Rehabilitation with Focal Vibration After Botulinum Toxin Injection in Ambulatory Children with Cerebral...

Cerebral palsy is a leading cause of childhood motor disability, and ambulatory children with spastic hemiplegia commonly present with dynamic equinus, calf muscle overactivity, and gait impairment. Evidence on focal vibration after botulinum toxin type A injection remains limited. This exploratory proof-of-concept pilot study assessed short-term changes following a four-week multimodal rehabilitation program incorporating focal vibration. In this uncontrolled single-group pre-post study, nine ambulatory children (mean age, 12.1 years), all classified as level II on the Gross Motor Function Classification System, received onabotulinumtoxinA injections into the affected gastrocnemius muscles, followed by twelve outpatient sessions combining focal vibration, conventional physiotherapy, and robotic gait training. Passive ankle dorsiflexion increased, calf muscle spasticity decreased, and selected gait parameters improved. Walking speed increased from 0.79 to 0.90 m per second, an absolute change of 0.11 m per second, comparable in magnitude to published estimates of clinically important change in ambulatory children with cerebral palsy. After Bonferroni correction, only walking speed and affected-limb stride length remained significant. No adverse events occurred. These findings describe outcomes associated with the combined program but do not establish the efficacy or independent contribution of focal vibration.