Related Experiment Video

Updated: Aug 28, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

Identification of Seven Novel HLA Alleles by Third Generation Sequencing

Ava H Sutherland1, Thomas R Turner1,2, Leonhard M Flaxl3

  • 1Anthony Nolan Research Institute, Royal Free Hospital, London, UK.

HLA
|August 26, 2026
PubMed

Abstract:

Seven novel HLA alleles were identified using PacBio Single Molecule, Real-Time (SMRT) DNA sequencing.

Keywords:
HLASMRT sequencingT cellnovel allelepolymorphism

More Related Videos

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
10:37

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix

Published on: October 20, 2021

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis
09:32

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis

Published on: October 15, 2021

Related Experiment Videos

Last Updated: Aug 28, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
10:37

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix

Published on: October 20, 2021

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis
09:32

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis

Published on: October 15, 2021

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

Articles linked to this work by shared authors, journal, and citation graph.

HLA matching in contemporary haematopoietic cell transplantation: Recommendations from the EBMT Practice Harmonisation and Guidelines Committee.

Bone marrow transplantation·2026

Identification of the Novel HLA-DRA*01:20 Allele by Single Molecule, Real-Time DNA Sequencing.

HLA·2026

Germ factories or immune boot camps? Infection and immunity in childcare settings.

Clinical microbiology reviews·2026

Full-Length Sequence Characterisation of the Novel MICB Null Allele, MICB*068N.

HLA·2026

Fifteen Novel HLA Class I Alleles Identified in Haematopoietic Cell Transplant Recipients and Donors.

HLA·2026

A Pilot Project to Evaluate the Benefit of Additional Support in Haematopoietic Cell Transplant (HCT) Research Data Management on Behalf of Anthony Nolan and BSBMTCT.

EJHaem·2026

Identification of the Novel HLA-G*01:01:39 Allele Using PolyseqOne Sequencing.

HLA·2026

Identification and Characterisation of a Novel HLA-DPB1*1985:01 Allele by Long-Read Sequencing.

HLA·2026

Discovery of the Novel KIR2DL1*00406 Allele Identified in a Chinese Han Individual.

HLA·2026

Characterisation of the Novel HLA-A*03:40:02 Allele by Next-Generation Sequencing.

HLA·2026

Identification of the Novel MICA*296 Allele in a Chinese Cord Blood Donor.

HLA·2026

Characterisation of the Novel HLA-DQB1*02:85:02 Allele by Sequencing-Based Typing.

HLA·2026

Identification and validation of feature genes using a ferroptosis-informed analytical framework in medulloblastoma.

Frontiers in pediatrics·2026

Genome-wide CRISPR screens identify shared and context-specific regulators of podocyte resistance to oxidative injury.

Renal failure·2026

Genotype and arrhythmic risk in dilated cardiomyopathy.

European heart journal·2026

Gene-Guided Therapy in Type 2 Diabetes Mellitus: An Integrative Review of the Pharmacogenetics of Metformin and Sodium-Glucose Cotransporter-2 Inhibitors.

Endocrinology, diabetes & metabolism·2026

Evaluating the effects of metronidazole, metformin, and onion extract on GAPDH activity and nitric oxide production in Blastocystis sp. cultures: a biochemical and therapeutic approach.

BMC complementary medicine and therapies·2026

Excess endopolyploidy associated with cellular defects in neo-autotetraploid Arabidopsis arenosa is in part corrected by a naturally evolved allele of CYCD3;2.

The New phytologist·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us