Disseminate and recurrent infundibulofolliculitis

Disseminate and recurrent infundibulofolliculitis is an uncommon pruitic papular follicular eruption that affects the trunk and proximal extremities and occurs almost exclusively in blacks. Little is known about the cause, and treatment has been totally unsuccessful. Extensive laboratory investigations, including histology and direct immunofluorescence in four cases, were unrevealing. Oral vitamin A therapy was effective in controlling five of six cases. We consider this disease to be a specific clinical and pathologic response to an, as yet, unknown cause or causes.