Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Apocrine cystadenoma. An ultrastructural study.

M O Hassan, M A Khan, T V Kruse

    Archives of Dermatology
    |February 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies.

    The Journal of pharmacology and experimental therapeutics·1995
    Same author

    Clinicopathological features and management of immunoproliferative small intestinal disease and primary small intestinal lymphoma in Pakistan.

    Medical and pediatric oncology·1995
    Same author

    The role of dose rate in the induction of micronuclei in deep-lung fibroblasts in vivo after exposure to cobalt-60 gamma rays.

    Radiation research·1995
    Same author

    Efficacy of ciprofloxacin in enteric fever: comparison of treatment duration in sensitive and multidrug-resistant Salmonella.

    The American journal of tropical medicine and hygiene·1995
    Same author

    Atrial arrhythmias and pacing after orthotopic heart transplantation: bicaval versus standard atrial anastomosis.

    British heart journal·1995
    Same author

    Nutritional evaluation of desi and kabuli chickpeas and their products commonly consumed in Pakistan.

    International journal of food sciences and nutrition·1995

    Electron microscopy revealed two cell types in apocrine cystadenoma: secretory and basal myoepithelial cells. Secretory cells exhibited lipid droplets and apical decapitation, suggesting apocrine secretion.

    Area of Science:

    • Electron microscopy
    • Cell biology
    • Histopathology

    Background:

    • Apocrine cystadenoma is a benign cystic neoplasm.
    • Understanding its cellular mechanisms is crucial for diagnosis.

    Observation:

    • Electron microscopy identified secretory and basal (myoepithelial) cells.
    • Secretory cells contained lipid droplets and shed apical cytoplasm fragments.
    • Basal cells displayed abundant tonofilaments but fewer myofilaments than normal.

    Findings:

    • The presence of apical cytoplasm fragments suggests an apocrine secretory mechanism (decapitation).
    • A merocrine secretory pathway was also observed.
    • Myoepithelial cells showed distinct filament composition compared to normal apocrine glands.

    Related Experiment Videos

    Implications:

    • This study elucidates the ultrastructural features and secretory mechanisms of apocrine cystadenoma.
    • Findings contribute to the differential diagnosis of cystic lesions.
    • Provides insights into myoepithelial cell differentiation in this context.